IGF-1 LR3

IGF-1 LR3

IGF-1 Receptor Agonist for In Vitro Research

IGF-1 LR3 (Long Arg3 Insulin-like Growth Factor-1) is a synthetic polypeptide analog of human IGF-1, engineered with a 13-amino acid N-terminal extension and a substitution of arginine at position 3. It targets the IGF-1 receptor (IGF1R), a transmembrane tyrosine kinase receptor, and is designed to reduce binding to IGF-binding proteins (IGFBPs), enhancing its stability and receptor interaction during assays.

This peptide is commonly used in in vitro research to study mitogenic signaling, PI3K/Akt pathway activation, and receptor phosphorylation cascades. The LR3 modifications extend the half-life and reduce sequestration by IGFBPs, improving assay reproducibility in cellular environments.

The linear polypeptide structure is produced via recombinant expression and purified to high homogeneity. Supplied in lyophilized form, it supports long-term stability and consistent reconstitution for research applications.

For In Vitro Research Use Only. Not for Human or Veterinary Application.

Specifications:

Form: Lyophilized Powder

Molecular Formula: C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₆

Molecular Weight: ~9111.00 g/mol

Purity: >99.9% (HPLC verified)

Storage: -20°C, protect from light and moisture

Intended Use:

This peptide is intended for in vitro research only by qualified professionals. It is not for human or veterinary use, and must not be used in food, drugs, diagnostics, or cosmetics.

Disclaimer:

This compound has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease. All use must follow institutional and regulatory guidelines.

All product photos are purely informational. Final packaging, labelling, and appearance may differ from the images displayed.

Terms of Sale:

By purchasing from Cernum Biosciences, the buyer expressly certifies that they are a qualified and licensed researcher or institution. All sales are final. The purchaser assumes full responsibility for handling, use, and regulatory compliance. The buyer acknowledges that all products are strictly for laboratory research use only, not for human or veterinary use, and assumes full legal responsibility for proper handling, storage, use, and compliance with all applicable federal, state, and local laws and regulations.